©PCI•2002
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PrincetonCHIRALPrincetonCHIRALPrincetonCHIRALPrincetonCHIRALPrincetonCHIRAL
...The PrincetonChiral phases, DNB-LEU or DNB-PHGLY, are prepared from N-3,5-dinitrobenzoyl protected derivatives of leucine or phenylgylcine.

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PrincetonCHIRAL
  PrincetonCHIRAL HPLC columns 100Å pore size 5 and 3 µm spherical particles the chiral phases, DNB-LEU or DNB-PHGLY, are prepared from N-3,5-dinitrobenzoyl protected derivatives of leucine or phenylgylcine, (which are then bonded to silica stationary phase). These phases are available in both the D- or the L- enantiomers of the amino acids. The unique feature of amino-acid-derived chiral phases is that the elution order of enantiomers in the sample is dependent on the D- or L- chirality of the bonded amino acid. Therefore, the order of elution can be controlled by appropriate selection of stationary phase. This can be of tremendous advantage for those samples which contain a large excess of one enantiomer, in which case it is desirable to have the minor component elute first.Many racemic acids and amines which cannot be resolved in their native form can be easily converted to amides or anilides which can be resolved by an amino-acid-derived chiral phase:


 
 
Aromatic alcohols

Aromatic amino acids

Aromatic amino alcohols

Aromatic thiols

Aromatic amines

Aromatic sulfoxides

Mandelic acid analogs
Aryl substituted phthalides

Aryl substituted lactams

Aryl substituted succinamides

Aryl substituted hydantoins

Aryl acetamides

Hydroxy-aryl phosphonates
 
   
[ 100Å - 5, 3µm ]   [ 100Å - 5, 3µm ]
   
 • 4.6 / 4.0 / 3.0 mm ID    • 2.0 mm column ID
     
Note
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PrincetonCHIRAL Columns [ 4.6mm / 4.0mm / 3.0mm ID - 100Å - 5, 3µm]
 Phases L[mm] µ 4.6mm Part# 4.0mm Part# 3.0mm Part# Price
  D-
 DNB-
LEU
250 5 250046-03511 250040-03511 250030-03511 $575
150 5 150046-03511 150040-03511 150030-03511 525
150 3 100046-03311 100040-03311 100030-03311 $575
100 3 050046-03311 050040-03311 050030-03311 525
           
  L-
 DNB-
LEU
250 5 250046-03512 250040-03512 250030-03512 $575
150 5 150046-03512 150040-03512 150030-03512 525
150 3 100046-03312 100040-03312 100030-03312 $575
100 3 050046-03312 050040-03312 050030-03312 525
           
  D-
 DNB-
PHGL
250 5 250046-03513 250040-03513 250030-03513 $575
150 5 150046-03513 150040-03513 150030-03513 525
150 3 100046-03313 100040-03313 100030-03313 $575
100 3 050046-03313 050040-03313 050030-03313 525
           
  L-
 DNB-
PHGLY
250 5 250046-03514 250040-03514 250030-03514 $575
150 5 150046-03514 150040-03514 150030-03514 525
150 3 100046-03314 100040-03314 100030-03314 $575
100 3 050046-03314 050040-03314 050030-03314 525
           
             
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PrincetonCHIRAL Columns [ 2.0mm column ID - 100Å - 5, 3µm ]
 Phases L[mm] µ 2.0mm Part# Price
  D-
 DNB-
LEU
250 5 250020-03511 $600
150 5 150020-03511 550
150 3 150020-03311 $625
100 3 100020-03311 575
       
  L-
 DNB-
LEU
250 5 250020-03512 $600
150 5 150020-03512 550
150 3 150020-03312 $625
100 3 100020-03312 300
       
  D-
 DNB-
PHGL
250 5 250020-03513 $600
150 5 150020-03513 550
150 3 150020-03313 $625
100 3 100020-03313 575
       
  L-
 DNB-
PHGLY
250 5 250020-03514 $600
150 5 150020-03514 550
150 3 150020-03314 $625
100 3 100020-03314 575
       
             
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